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Article

Mutation and expression of the beta-catenin-interacting protein ICAT in human colorectal tumors.

Japanese journal of clinical oncology - 1 Sept 2002

Koyama Toru, Tago Ken-Ichi, Nakamura Tsutomu, Ohwada Susumu, Morishita Yasuo, Yokota Jun, Akiyama Tetsu

Abstract excerpt

BACKGROUND: Aberrant activation of Wnt signaling caused by mutations in the tumor suppressor adenomatous polyposis coli or beta-catenin is a critical event in the development of human colorectal tumors. We have recently identified the ICAT gene, which encodes a small protein that interacts with b...

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Identifiers

PMID: 12417602
DOI: 10.1093/jjco/hyf068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12417602-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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