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Article

Relating molecular flexibility to function: a case study of tubulin.

Biophysical journal - 1 Aug 2002

Keskin Ozlem, Durell Stewart R, Bahar Ivet, Jernigan Robert L, Covell David G

Abstract excerpt

Microtubules (MT), along with a variety of associated motor proteins, are involved in a range of cellular functions including vesicle movement, chromosome segregation, and cell motility. MTs are assemblies of heterodimeric proteins, alpha beta-tubulins, the structure of which has been determined by electron crystallography of zinc-induced, pacilitaxel-stabilized tubulin sheets. These data provide a basis for...

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Identifiers

PMID: 12124255
DOI: 10.1016/S0006-3495(02)75199-0
PMCID: PMC1302177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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