Article
A major susceptibility gene for asthma maps to chromosome 14q24.
American journal of human genetics - 1 Sept 2002
Hakonarson Hakon, Bjornsdottir Unnur S, Halapi Eva, Palsson Snaebjorn, Adalsteinsdottir Elva, Gislason David, Finnbogason Gudmundur, Gislason Thorarinn, Kristjansson Kristleifur, Arnason Thor, Birkisson Illugi, Frigge Michael L, Kong Augustine, Gulcher Jeffrey R, Stefansson Kari
Abstract excerpt
Asthma is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. Numerous loci and candidate genes have been reported to show linkage and association to asthma and atopy. Although some studies reporting these observations are compelling, no gene has been mapped that confers a sufficiently high risk of asthma...
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