Article
Positional cloning of a novel gene influencing asthma from chromosome 2q14.
Nature genetics - 1 Nov 2003
Allen Maxine, Heinzmann Andrea, Noguchi Emiko, Abecasis Gonçalo, Broxholme John, Ponting Chris P, Bhattacharyya Sumit, Tinsley Jon, Zhang Youming, Holt Richard, Jones E Yvonne, Lench Nick, Carey Alisoun, Jones Helene, Dickens Nicholas J, Dimon Claire, Nicholls Rosie, Baker Crystal, Xue Luzheng, Townsend Elizabeth, Kabesch Michael, Weiland Stephan K, Carr David, von Mutius Erika, Adcock Ian M, Barnes Peter J, Lathrop G Mark, Edwards Mark, Moffatt Miriam F, Cookson William O C M
Abstract excerpt
Asthma is a common disease in children and young adults. Four separate reports have linked asthma and related phenotypes to an ill-defined interval between 2q14 and 2q32 (refs. 1-4), and two mouse genome screens have linked bronchial hyper-responsiveness to the region homologous to 2q14 (refs. 5,...
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