Article
Role of the high-affinity zinc uptake znuABC system in Salmonella enterica serovar typhimurium virulence.
Infection and immunity - 1 Aug 2002
Campoy Susana, Jara Mónica, Busquets Núria, Pérez De Rozas Ana M, Badiola Ignacio, Barbé Jordi
Abstract excerpt
The Salmonella enterica serovar Typhimurium znuABC genes encoding a high-affinity zinc uptake system and its regulatory zur gene have been cloned. Salmonella serovar Typhimurium zur and znuC knockout mutants have been constructed by marker exchange. The 50% lethal dose of the znuC mutant increased when either orally or intraperitoneally inoculated in BALB/c mice, while virulence of the zur mutant decreased only...
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