Article
Zinc is required to ensure the expression of flagella and the ability to form biofilms in Salmonella enterica sv Typhimurium.
Metallomics : integrated biometal science - 1 Oct 2016
Ammendola Serena, D'Amico Ylenia, Chirullo Barbara, Drumo Rosanna, Ciavardelli Domenico, Pasquali Paolo, Battistoni Andrea
Abstract excerpt
Zinc is known to play a central role in bacterial physiology and pathogenesis. Here, we report that the accumulation of FliC, the structural subunit of Salmonella phase 1 flagella, is sharply reduced in a znuABC Salmonella enterica sv. Typhimurium strain grown in zinc-poor media. Consequently, this mutant strain lacks motility, unless it grows in zinc-replete environments. This phenotype is the consequence of a...
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