Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-Affinity Zn2+Uptake System ZnuABC Is Required for Bacterial Zinc Homeostasis in Intracellular Environments and Contributes to the Virulence ofSalmonella enterica

9 Oct 2007

Abstract excerpt

To investigate the relevance of zinc in host-pathogen interactions, we have constructed Salmonella enterica mutant strains in which the znuA gene, which encodes the periplasmic component of the ZnuABC high-affinity Zn2+ transporter, was deleted. This mutation does not alter the ability of Salmonella to grow in rich media but drastically reduces its ability to multiply in media deprived of zinc. In agreement with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Iron Metabolism and Disorders
Share to Salmonella and Campylobacter epidemiology
Share to Trace Elements in Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17923515
DOI: 10.1128/iai.00559-07

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-Affinity Zn2+Uptake System ZnuABC Is Required for Bacterial Zinc Homeostasis in Intracellular Environments and Contributes to the Virulence ofSalmonella entericaPMID 17923515Read ↗

Phenotypic profile linked to inhibition of the major Zn influx system in Salmonella enterica: proteomics and ionomics investigations.Semantic proximity Read ↗

A Novel Antimicrobial Approach Based on the Inhibition of Zinc Uptake in Salmonella EntericaSemantic proximity Read ↗

Competition for zinc binding in the host-pathogen interactionSemantic proximity Read ↗

Zinc is required to ensure the expression of flagella and the ability to form biofilms in Salmonella enterica sv Typhimurium.Semantic proximity Read ↗

Zinc Homeostasis at the Bacteria/Host Interface—From Coordination Chemistry to Nutritional ImmunitySemantic proximity Read ↗

Role of the high-affinity zinc uptake znuABC system in Salmonella enterica serovar typhimurium virulence.Semantic proximity Read ↗

The role of metal ions in the virulence and viability of bacterial pathogensSemantic proximity Read ↗

The AdcACB/AdcAII system is essential for zinc homeostasis and an important contributor of Enterococcus faecalis virulenceSemantic proximity Read ↗

Cellular management of Zinc in group B <i>Streptococcus</i> supports bacterial resistance against metal intoxication and promotes disseminated infectionSemantic proximity Read ↗

Zinc uptake system ZnuACB is essential for maintaining pathogenic phenotype of F4ac+ enterotoxigenic E. coli (ETEC) under a zinc restricted environment.Semantic proximity Read ↗

Zinc transporters YbtX and ZnuABC are required for the virulence of Yersinia pestis in bubonic and pneumonic plague in mice.Semantic proximity Read ↗

Znu is the predominant zinc importer in Yersinia pestis during in vitro growth but is not essential for virulence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.