Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Znu is the predominant zinc importer in Yersinia pestis during in vitro growth but is not essential for virulence.

Infection and immunity - 1 Dec 2010

Desrosiers Daniel C, Bearden Scott W, Mier Ildefonso, Abney Jennifer, Paulley James T, Fetherston Jacqueline D, Salazar Juan C, Radolf Justin D, Perry Robert D

Abstract excerpt

Little is known about Zn homeostasis in Yersinia pestis, the plague bacillus. The Znu ABC transporter is essential for zinc (Zn) uptake and virulence in a number of bacterial pathogens. Bioinformatics analysis identified ZnuABC as the only apparent high-affinity Zn uptake system in Y. pestis. Mutation of znuACB caused a growth defect in Chelex-100-treated PMH2 growth medium, which was alleviated by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP-Binding Cassette Transporters
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Middle East

Share to Plague

Share to Virulence

Share to Yersinia pestis

Source

Open in PubMed Open full text

Identifiers

PMID: 20855510
DOI: 10.1128/IAI.00732-10
PMCID: PMC2981304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Znu is the predominant zinc importer in Yersinia pestis during in vitro growth but is not essential for virulence.PMID 20855510Read ↗

The Y ersinia pestis siderophore, yersiniabactin, and the ZnuABC system both contribute to zinc acquisition and the development of lethal septicaemic plague in miceSemantic proximity Read ↗

Zinc transporters YbtX and ZnuABC are required for the virulence of Yersinia pestis in bubonic and pneumonic plague in mice.Semantic proximity Read ↗

Competition for zinc binding in the host-pathogen interactionSemantic proximity Read ↗

Zinc uptake system ZnuACB is essential for maintaining pathogenic phenotype of F4ac+ enterotoxigenic E. coli (ETEC) under a zinc restricted environment.Semantic proximity Read ↗

The high-affinity zinc-uptake system znuACB is under control of the iron-uptake regulator (fur) gene in the animal pathogen Pasteurella multocida.Semantic proximity Read ↗

Zinc Acquisition Mechanisms Differ between Environmental and Virulent Francisella Species.Semantic proximity Read ↗

Zinc Homeostasis at the Bacteria/Host Interface—From Coordination Chemistry to Nutritional ImmunitySemantic proximity Read ↗

High-Affinity Zn2+Uptake System ZnuABC Is Required for Bacterial Zinc Homeostasis in Intracellular Environments and Contributes to the Virulence ofSalmonella entericaSemantic proximity Read ↗

Phenotypic profile linked to inhibition of the major Zn influx system in Salmonella enterica: proteomics and ionomics investigations.Semantic proximity Read ↗

Uropathogenic enterobacteria use the yersiniabactin metallophore system to acquire nickelSemantic proximity Read ↗

ZccE is a Novel P-type ATPase That Protects <i>Streptococcus mutans</i> Against Zinc IntoxicationSemantic proximity Read ↗

Strategies for Zinc Uptake in Pseudomonas aeruginosa at the Host–Pathogen InterfaceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.