Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Involvement of SipA in modulating actin dynamics during Salmonella invasion into cultured epithelial cells.

Cellular microbiology - 1 Jun 2002

Higashide Wendy, Dai Shipan, Hombs Veronica P, Zhou Daoguo

Abstract excerpt

Salmonella entry into epithelial host cells results from the host actin cytoskeleton reorganization that is induced by a group of bacterial proteins delivered to the host cells by the Salmonella type III secretion system. SopE, SopE2 and SopB activate CDC42 and Rac1 to intercept the signal transduction pathways involved in actin cytoskeleton rearrangements. SipA and SipC directly bind actin to modulate the actin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Actins
Share to Caco-2 Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COS Cells

Share to Cytoskeleton

Share to Epithelium

Share to Microfilament Proteins

Share to Salmonella enterica

Source

Identifiers

PMID: 12116966
DOI: 10.1046/j.1462-5822.2002.00196.x

Genes

CDC42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Involvement of SipA in modulating actin dynamics during Salmonella invasion into cultured epithelial cells.PMID 12116966Read ↗

Role of the S. typhimurium actin-binding protein SipA in bacterial internalization.Semantic proximity Read ↗

Role of sipA in the early stages of Salmonella typhimurium entry into epithelial cells.Semantic proximity Read ↗

A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.Semantic proximity Read ↗

RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42.Semantic proximity Read ↗

SanA is an inner membrane protein mediating the early stages of Salmonella infectionSemantic proximity Read ↗

IpaA targets beta1 integrins and rho to promote actin cytoskeleton rearrangements necessary for Shigella entry.Semantic proximity Read ↗

Salmonella modulates vesicular traffic by altering phosphoinositide metabolism.Semantic proximity Read ↗

SopB-Mediated Recruitment of SNX18 Facilitates Salmonella Typhimurium Internalization by the Host Cell.Semantic proximity Read ↗

IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells.Semantic proximity Read ↗

Invasion and intracellular proliferation of Salmonella within non-phagocytic cells.Semantic proximity Read ↗

The amino-terminal non-catalytic region of Salmonella typhimurium SigD affects actin organization in yeast and mammalian cells.Semantic proximity Read ↗

Killing of Candida albicans filaments by Salmonella enterica serovar Typhimurium is mediated by sopB effectors, parts of a type III secretion system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.