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Article

Salmonella modulates vesicular traffic by altering phosphoinositide metabolism.

Science (New York, N.Y.) - 18 Jun 2004

Hernandez Lorraine D, Hueffer Karsten, Wenk Markus R, Galán Jorge E

Abstract excerpt

Salmonella enterica, the cause of food poisoning and typhoid fever, induces actin cytoskeleton rearrangements and membrane ruffling to gain access into nonphagocytic cells, where it can replicate and avoid innate immune defenses. Here, we found that SopB, a phosphoinositide phosphatase that is delivered into host cells by a type III secretion system, was essential for the establishment of Salmonella's...

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Identifiers

PMID: 15205533
DOI: 10.1126/science.1098188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Salmonella modulates vesicular traffic by altering phosphoinositide metabolism.PMID 15205533Read ↗

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What the SIF Is Happening—The Role of Intracellular Salmonella-Induced FilamentsSemantic proximity Read ↗

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