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Article

SopB-Mediated Recruitment of SNX18 Facilitates Salmonella Typhimurium Internalization by the Host Cell.

Frontiers in cellular and infection microbiology - 1 Jan 2017

Liebl David, Qi Xiaying, Zhe Yang, Barnett Timothy C, Teasdale Rohan D

Abstract excerpt

To invade epithelial cells, Salmonella enterica serovar Typhimurium (S. Typhimurium) induces macropinocytosis through the action of virulence proteins delivered across the host cell membrane via a type III secretion system. We show that after docking at the plasma membrane S. Typhimurium triggers rapid recruitment of cytosolic SNX18, a SH3-PX-BAR domain sorting nexin protein, to the bacteria-induced membrane...

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Identifiers

PMID: 28664153
DOI: 10.3389/fcimb.2017.00257
PMCID: PMC5471308

Genes

SNX18

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