Article
The mammalian transcriptional repressor RBP (CBF1) regulates interleukin-6 gene expression.
Molecular and cellular biology - 1 Jan 1997
Kannabiran C, Zeng X, Vales L D
Abstract excerpt
The cellular interleukin-6 (IL-6) gene contains a target site for the mammalian transcriptional repressor RBP. The target site is contained within the interleukin response element (ILRE), which mediates IL-6 activation by NF-kappa B. In this study, we show by using transient-expression assays that RBP represses activated transcription from the IL-6 gene. The presence and position of the RBP target site are...
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