Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The insulin gene VNTR polymorphism in Alzheimer's disease: results of a pilot study.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jul 2002

Majores M, Kölsch Heiki, Bagli M, Ptok U, Kockler M, Becker K, Rao M L, Maier W, Heun R

Abstract excerpt

Insulin (INS) and insulin-like growth factors include different polypeptides involved in growth and development. Possibly they play a role in the pathogenesis of neurodegenerative disorders such as Alzheimer's disease (AD). A variable number of tandem repeats (VNTR) polymorphism at the human INS 5'-flanking region consisting of three distinct allele classes has been shown to influence the tissue-specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Homozygote

Share to Insulin

Share to Minisatellite Repeats

Share to Pilot Projects

Share to Survival Analysis

Source

Identifiers

PMID: 12111440
DOI: 10.1007/s007020200086

Genes

INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The insulin gene VNTR polymorphism in Alzheimer's disease: results of a pilot study.PMID 12111440Read ↗

IGF-I gene variability is associated with an increased risk for AD.Semantic proximity Read ↗

Potential roles of insulin and IGF-1 in Alzheimer's diseaseSemantic proximity Read ↗

Insulin-like growth factor–1 and risk of late-onset Alzheimer's disease: findings from a family studySemantic proximity Read ↗

Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project.Semantic proximity Read ↗

Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease.Semantic proximity Read ↗

Insulin-degrading enzyme is genetically associated with Alzheimer’s disease in the Finnish populationSemantic proximity Read ↗

Insulin metabolism and the risk of Alzheimer disease: the Rotterdam Study.Semantic proximity Read ↗

Disorder-specific effects of polymorphisms at opposing ends of the Insulin Degrading Enzyme gene.Semantic proximity Read ↗

Association of insulin-like growth factor-1 receptor polymorphism in dementia.Semantic proximity Read ↗

Serum insulin‐like system alterations in patients with spinocerebellar ataxia type 3Semantic proximity Read ↗

Association analysis between longevity in the Japanese population and polymorphic variants of genes involved in insulin and insulin-like growth factor 1 signaling pathways.Semantic proximity Read ↗

The IRS2 Gly1057Asp variant is associated with human longevity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.