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Article

<b>β</b>7 Integrin expression is not required for the localization of T cells to the intestine and colitis pathogenesis

28 Jun 2002

Abstract excerpt

beta7 Integrins have been shown to have an important role in the localization of T cells to the intestine. Utilizing two different experimental mouse models of inflammatory bowel disease (IBD), this study was undertaken to determine if beta7 integrin expression is critical for T cell localization to the intestine and colitis pathogenesis. Transfer of CD4+ CD45RBhigh cells into immunodeficient mice results in...

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PMID: 12100020
DOI: 10.1046/j.1365-2249.2002.01892.x

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