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Article

Beta2 integrins and ICAM-1 are involved in establishment of the intestinal mucosal T cell compartment.

Immunity - 1 Sept 1996

Huleatt J W, Lefrançois L

Abstract excerpt

Development of the mucosal immune system was examined in mice with partial loss of expression of ICAM-1 or CD18. Profound effects on Peyer's patch (PP), lamina propria (LP), and intraepithelial lymphocyte (IEL) T cell populations were observed in mutant mice. Normal expression of CD18 integrins and ICAM-1 was essential for development of the CD8(alpha beta) TCR(alpha beta)LP and IEL compartment and for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8808681
DOI: 10.1016/s1074-7613(00)80321-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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