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Article

Sleep/wake cycle disturbance in Alzheimer's disease: how much is due to an inherent trait?

International psychogeriatrics - 1 Mar 2002

Yesavage Jerome A, Taylor Joy L, Kraemer Helena, Noda Art, Friedman Leah, Tinklenberg Jared R

Abstract excerpt

Major advances in understanding the physiology and genetics of circadian rhythm in the past decade challenge the researcher of sleep/wake disorders in Alzheimer's disease (AD) to distinguish patient characteristics stable across the course of illness ("traits") from characteristics that vary with stage of illness ("states"). A components-of-variance approach with a repeated measures model was used to examine the...

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PMID: 12094910
DOI: 10.1017/s1041610202008293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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