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Article

Sleep/wake disruption in Alzheimer's disease: APOE status and longitudinal course.

Journal of geriatric psychiatry and neurology - 1 Mar 2004

Yesavage Jerome A, Friedman Leah, Kraemer Helena, Tinklenberg Jared R, Salehi Ahmad, Noda Art, Taylor Joy L, O'Hara Ruth, Murphy Greer

Abstract excerpt

Disturbed sleep is a major clinical problem in Alzheimer's disease (AD). Apolipoprotein epsilon4 (APOE epsilon4) carrier status may increase risk of AD, yet there are no data on relations between APOE status and progression of sleep disturbance in AD. The objective of this study was to determine if sleep parameters in AD patients change over time as a function of APOE carrier status. Forty-four community-dwelling...

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Source

Identifiers

PMID: 15018693
DOI: 10.1177/0891988703261994

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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