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Article

Circadian clock gene polymorphisms and sleep-wake disturbance in Alzheimer disease.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Jul 2011

Yesavage Jerome A, Noda Art, Hernandez Beatriz, Friedman Leah, Cheng Jauhtai J, Tinklenberg Jared R, Hallmayer Joachim, O'hara Ruth, David Renaud, Robert Philippe, Landsverk Elizabeth, Zeitzer Jamie M

Abstract excerpt

OBJECTIVES: One of the hypothesized causes of the breakdown in sleep-wake consolidation often occurring in individuals with Alzheimer disease (AD) is the dysfunction of the circadian clock. The goal of this study is to report indices of sleep-wake function collected from individuals with AD in relation to relevant polymorphisms in circadian clock-related genes. DESIGN: One week of ad libitum ambulatory sleep data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21709609
DOI: 10.1097/JGP.0b013e31820d92b2
PMCID: PMC3128424

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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