Article
Sleep-wake disorders in Alzheimer's disease: further genetic analyses in relation to objective sleep measures.
International psychogeriatrics - 1 Jul 2020
Yesavage Jerome A, Noda Art, Heath Alesha, McNerney M Windy, Domingue Benjamin W, Hernandez Yozen, Benson Gary, Hallmayer Joachim, O'Hara Ruth, Williams Leanne M, Goldstein-Piekarski Andrea N, Zeitzer Jamie M, Fairchild J Kaci
Abstract excerpt
This paper presents updated analyses on the genetic associations of sleep disruption in individuals with Alzheimer's disease (AD). We published previously a study of the association between single nucleotide polymorphisms (SNPs) found in eight genes related to circadian rhythms and objective measures of sleep-wake disturbances in 124 individuals with AD. Here, we present new relevant analyses using polygenic risk...
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