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Article

Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice.

Molecular and cellular neurosciences - 1 Jun 2002

Pavlov Ivan, Võikar Vootele, Kaksonen Marko, Lauri Sari E, Hienola Anni, Taira Tomi, Rauvala Heikki

Abstract excerpt

Heparin-binding growth-associated molecule (HB-GAM) is an extracellular matrix-associated protein with neurite outgrowth-promoting activity and which is suggested to be implicated in hippocampal synaptic plasticity. To study the functions of HB-GAM in adult brain we have produced HB-GAM overexpressing mice and compared phenotypic changes in the transgenic mice to those in the HB-GAM null mice. Both mutants were...

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Identifiers

PMID: 12093164
DOI: 10.1006/mcne.2002.1104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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