Article
Osteoblast recruitment and bone formation enhanced by cell matrix-associated heparin-binding growth-associated molecule (HB-GAM).
The Journal of cell biology - 16 Nov 1998
Imai S, Kaksonen M, Raulo E, Kinnunen T, Fages C, Meng X, Lakso M, Rauvala H
Abstract excerpt
Bone has an enormous capacity for growth, regeneration, and remodeling. This capacity is largely due to induction of osteoblasts that are recruited to the site of bone formation. The recruitment of osteoblasts has not been fully elucidated, though the immediate environment of the cells is likely...
Topics
- Animals
- Bone Development
- Carrier Proteins
- Cell Differentiation
- Cells, Cultured
- Cytokines
- Extracellular Matrix Proteins
- Gene Expression Regulation, Developmental
- Membrane Glycoproteins
- Mice
- Mice, Transgenic
- Microscopy, Immunoelectron
- Mitogens
- Ossification, Heterotopic