Article
-174 G/C interleukin-6 gene polymorphism and increased risk of multi-infarct dementia: a case-control study.
Experimental gerontology - 1 Jul 2002
Pola Roberto, Gaetani Eleonora, Flex Andrea, Aloi Francesco, Papaleo Pierangelo, Gerardino Laura, De Martini Demetrio, Flore Roberto, Pola Paolo, Bernabei Roberto
Abstract excerpt
The aim of this study was to evaluate the association between the -174 G/C polymorphism of interleukin-6 (IL-6) gene promoter and multi-infarct dementia (MID). We studied a group of 122 patients affected by MID and 134 age- and sex-matched controls and evaluated classical risk factors for MID, as well as the distribution of IL-6 alleles and genotypes by polymerase chain reaction and restriction enzyme analysis....
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