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Article

Arthritis induced in rats with non‐immunogenic adjuvants as models for rheumatoid arthritis

1 Dec 2001

Abstract excerpt

Rat models are useful for studies of the pathogenesis of rheumatoid arthritis (RA) since rats are extraordinarily sensitive to induction of arthritis with adjuvants. Injection of not only the classical complete Freund's adjuvant but also mineral oil without mycobacteria and pure adjuvants such as pristane and squalene, induce severe arthritis in many rat strains. Models like pristane-induced arthritis in rats are...

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PMID: 12086312
DOI: 10.1034/j.1600-065x.2001.1840117.x

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