Mouse models of autoimmune diseases.

doi:10.2174/157016309789869047

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Article

Mouse models of autoimmune diseases.

Current drug discovery technologies - 1 Dec 2009

Marques Andreia, Müller Susen

Abstract excerpt

Significant progress has been made in past decades in our understanding of the basic mechanisms underlying autoimmune diseases. Nevertheless, many questions remain unanswered, in particular regarding the mechanisms at very early stages of these diseases. Reliable animal models are of crucial importance in basic research and may help us to understand central disease pathways. They are also indispensable for...

Topics

Animals
Antirheumatic Agents
Arthritis, Experimental
Arthritis, Rheumatoid
Autoimmune Diseases
Disease Models, Animal
Drug Evaluation, Preclinical
Encephalomyelitis, Autoimmune, Experimental
Genetic Predisposition to Disease
Humans
Immunosuppressive Agents
Mice
Models, Immunological
Multiple Sclerosis

Source

Open in PubMed

Identifiers

PMID: 20025594
DOI: 10.2174/157016309789869047

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