Article
Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia.
Molecular psychiatry - 1 Jan 2002
Anney R J, Rees M I, Bryan E, Spurlock G, Williams N, Norton N, Williams H, Cardno A, Zammit S, Jones S, Jones G, Hoogendoorn B, Smith K, Hamshere M L, Coleman S, Guy C, O'Donovan M C, Owen M J, Buckland P R
Abstract excerpt
The dopamine D(3) receptor gene (DRD3) is a candidate for a number of psychiatric conditions including schizophrenia, bipolar disorder and alcohol and drug abuse. Previous studies have reported associations between polymorphisms in DRD3 and these disorders, but these findings may have reflected linkage disequilibrium with pathogenic variants that are further upstream. We have isolated and sequenced approximately...
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