Article
Association study of schizophrenia and the dopamine D3 receptor gene locus in two independent samples.
American journal of medical genetics - 22 Nov 1996
Nimgaonkar V L, Sanders A R, Ganguli R, Zhang X R, Brar J, Hogge W, Fann W E, Patel P I, Chakravarti A
Abstract excerpt
Using a case-control design, an association of schizophrenia with the dopamine D3 receptor gene (D3RG) locus was investigated. Initial analysis of pooled results from published studies revealed a significant excess of individuals homozygous for either allele among the patients. The association was next tested in two cohorts ascertained independently at Pittsburgh, Pennsylvania and at Houston, Texas. The...
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