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Article

Transforming growth factor-beta mediates balance between inflammation and fibrosis during plaque progression.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2002

Lutgens Esther, Gijbels Marion, Smook Marjan, Heeringa Peter, Gotwals Philip, Koteliansky Victor E, Daemen Mat J A P

Abstract excerpt

The transition from stable to rupture-prone and ruptured atherosclerotic plaques involves many processes, including an altered balance between inflammation and fibrosis. An important mediator of both is transforming growth factor (TGF)-beta, and a pivotal role for TGF-beta in atherogenesis has be...

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Source

Identifiers

PMID: 12067907
DOI: 10.1161/01.atv.0000019729.39500.2f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12067907-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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