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Article

Regression and stabilization of advanced murine atherosclerotic lesions: a comparison of LDL lowering and HDL raising gene transfer strategies.

Journal of molecular medicine (Berlin, Germany) - 1 Jun 2011

Van Craeyveld Eline, Gordts Stephanie C, Nefyodova Elena, Jacobs Frank, De Geest Bart

Abstract excerpt

Both reductions in atherogenic lipoproteins and increases in high-density lipoprotein (HDL) levels may affect atherosclerosis regression. Here, the relative potential of low-density lipoprotein (LDL) lowering and HDL raising gene transfer strategies to induce regression of complex murine atherosclerotic lesions was directly compared. Male C57BL/6 LDL receptor (LDLr)(-/-) mice were fed an atherogenic diet (1.25%...

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Share to Adenoviridae
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein A-I

Share to Diet, Atherogenic

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Share to Lipoproteins, LDL

Share to Plaque, Atherosclerotic

Source

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Identifiers

PMID: 21249329
DOI: 10.1007/s00109-011-0722-x
PMCID: PMC3098380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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