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Article

TGF-β and atherosclerosis in man

26 Feb 2007

Abstract excerpt

The transforming growth factor type-beta (TGF-beta) superfamily of ligands, receptors, binding proteins and ligand traps together plays a key role in the maintenance of normal blood vessel wall structure. Specific defects in genes encoding superfamily members have now been linked to a range of cardiovascular syndromes involving loss of healthy vessel architecture, including hypertension and aneurysm. However the...

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PMID: 17382916
DOI: 10.1016/j.cardiores.2007.02.022

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