Article
Subendothelial retention of atherogenic lipoproteins in early atherosclerosis.
Nature - 13 Jun 2002
Skålén Kristina, Gustafsson Maria, Rydberg Ellen Knutsen, Hultén Lillemor Mattsson, Wiklund Olov, Innerarity Thomas L, Borén Jan
Abstract excerpt
Complications of atherosclerosis are the most common cause of death in Western societies. Among the many risk factors identified by epidemiological studies, only elevated levels of lipoproteins containing apolipoprotein (apo) B can drive the development of atherosclerosis in humans and experimental animals even in the absence of other risk factors. However, the mechanisms that lead to atherosclerosis are still...
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