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Article

Apo A-I inhibits foam cell formation in Apo E-deficient mice after monocyte adherence to endothelium.

The Journal of clinical investigation - 1 Jul 1999

Dansky H M, Charlton S A, Barlow C B, Tamminen M, Smith J D, Frank J S, Breslow J L

Abstract excerpt

We have previously shown that expression of the human apo A-I transgene on the apo E-deficient background increases HDL cholesterol and greatly diminishes fatty streak lesion formation. To examine the mechanism, prelesional events in atherosclerotic plaque development were examined in 6- to 8-week-old apo E-deficient and apo E-deficient/human apo A-I transgenic mice. A quantitative assessment of subendothelial...

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Identifiers

PMID: 10393696
DOI: 10.1172/JCI6577
PMCID: PMC408406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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