Article
Beta-globin gene cluster haplotypes as evidence of African gene flow to the northeastern coast of Venezuela.
American journal of human biology : the official journal of the Human Biology Council - 1 Jan 2000
Vívenes De Lugo Merlyn, Rodríguez-Larralde Alvaro, Castro De Guerra Dinorah
Abstract excerpt
In order to study the origin of mutation HBB*S in Sucre and Anzoátegui states and the genetic affinities of these Venezuelan populations with other human groups, the beta-globin gene cluster haplotypes were determined for 28 sickle cell and/or S-beta thalassemia patients and for 37 individuals with normal hematological parameters. Bantu, Benin, Senegal, and atypical haplotypes were identified in 50%, 36%, 2%, and...
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