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Article

Upregulation of IL-13 concentration in vivo by the IL13 variant associated with bronchial asthma.

The Journal of allergy and clinical immunology - 1 Jun 2002

Arima Kazuhiko, Umeshita-Suyama Ritsuko, Sakata Yasuhisa, Akaiwa Mina, Mao Xiao-Quan, Enomoto Tadao, Dake Yoshio, Shimazu Shin-ichiro, Yamashita Tetsuji, Sugawara Naoto, Brodeur Scott, Geha Raif, Puri Raj K, Sayegh Mohamad H, Adra Chaker N, Hamasaki Naotaka, Hopkin Julian M, Shirakawa Taro, Izuhara Kenji

Abstract excerpt

BACKGROUND: A substantial body of evidence exists to support the pivotal role of IL-13 in the pathogenesis of bronchial asthma. We recently found that a variant of the IL13 gene (Arg110Gln) is genetically associated with bronchial asthma, which is concordant with animal experiments using IL-13 in...

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Identifiers

PMID: 12063528
DOI: 10.1067/mai.2002.124656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12063528-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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