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Article

Effect of IL-13 receptor alpha2 levels on the biological activity of IL-13 variant R110Q.

The Journal of allergy and clinical immunology - 1 Jul 2007

Andrews Allison-Lynn, Bucchieri Fabio, Arima Kazuhiko, Izuhara Kenji, Holgate Stephen T, Davies Donna E, Holloway John W

Abstract excerpt

BACKGROUND: IL-13 is a key cytokine associated with the asthmatic phenotype. IL-13 signals via its cognate receptor, a complex of IL-13 receptor (IL-13R) alpha 1 chain with IL-4 receptor alpha; however, a second protein, IL-13Ralpha2, also binds IL-13. Recently a polymorphic variant of IL-13 (R11...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17560640
DOI: 10.1016/j.jaci.2007.04.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17560640-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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