Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Specific Cleavage of Hepatitis C Virus RNA Genome by Human RNase P

1 Aug 2002

Abstract excerpt

We have found that RNase P from HeLa cells specifically and efficiently cleaves hepatitis C virus (HCV) transcripts in vitro. The evidence includes identification of the 5'-phosphate polarity of the newly generated termini at position A(2860) as well as immunological and biochemical assays. Active cleavage has been shown in five dominant sequences of HCV "quasispecies" differing at or near the position of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12060655
DOI: 10.1074/jbc.m203595200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Specific Cleavage of Hepatitis C Virus RNA Genome by Human RNase PPMID 12060655Read ↗

Characterizing the function and structural organization of the 5' tRNA-like motif within the hepatitis C virus quasispecies.Semantic proximity Read ↗

Detection of tRNA-like Structure through RNase P Cleavage of Viral Internal Ribosome Entry Site RNAs Near the AUG Start TripletSemantic proximity Read ↗

RNase L releases a small RNA from HCV RNA that refolds into a potent PAMPSemantic proximity Read ↗

RNA Recognition and Cleavage by the SARS Coronavirus EndoribonucleaseSemantic proximity Read ↗

RNA self-cleavage activated by ultraviolet light-induced oxidation.Semantic proximity Read ↗

Processing of the hepatitis E virus polyprotein can be mediated by a cellular proteaseSemantic proximity Read ↗

Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III inStreptococcus pyogenesSemantic proximity Read ↗

A putative loop E motif and an H-H kissing loop interaction are conserved and functional features in a group C enterovirus RNA that inhibits ribonuclease L.Semantic proximity Read ↗

Hepatitis G virus encodes protease activities which can effect processing of the virus putative nonstructural proteins.Semantic proximity Read ↗

Catalytic RNase P RNA from Synechocystis sp. cleaves the hepatitis C virus RNA near the AUG start codon.Semantic proximity Read ↗

Engineered RNase P ribozymes inhibit gene expression and growth of cytomegalovirus by increasing rate of cleavage and substrate binding.Semantic proximity Read ↗

Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.