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Article

Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA

1 Jun 1996

Abstract excerpt

Previous reports suggest that the hepatitis C virus (HCV) genome RNA terminates with homopolymer tracts of either poly(U) or poly(A). By ligation of synthetic oligonucleotides followed by reverse transcription-PCR, cDNA cloning, and sequence analysis, we determined the 3'-terminal sequence of HCV genome RNA. Our results show that the HCV 3' nontranslated region consists of four elements (positive sense, 5' to...

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PMID: 8648666
DOI: 10.1128/jvi.70.6.3363-3371.1996

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Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNAPMID 8648666Read ↗

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