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Article

RNA self-cleavage activated by ultraviolet light-induced oxidation.

Nucleic acids research - 1 Feb 2012

Ariza-Mateos Ascensión, Prieto-Vega Samuel, Díaz-Toledano Rosa, Birk Alex, Szeto Hazel, Mena Ignacio, Berzal-Herranz Alfredo, Gómez Jordi

Abstract excerpt

A novel UV-C-light-induced ribozyme activity was discovered within the highly structured 5'-genomic regions of both Hepatitis C Virus (HCV) and the related Classic Swine Fever Virus (CSFV). Cleavage is mediated by exposure to UV-C light but not by exogenous oxygen radicals. It is also very selective, occurring at base positions HCV C(79) and CSFV A(45) in some molecules and at the immediately adjacent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21989404
DOI: 10.1093/nar/gkr822
PMCID: PMC3287179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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