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Article

Parental genotypes in the risk of a complex disease.

American journal of human genetics - 1 Jul 2002

Labuda Damian, Krajinovic Maja, Sabbagh Audrey, Infante-Rivard Claire, Sinnett Daniel

Abstract excerpt

Our understanding of the genetic etiology of complex disorders is still elusive. According to the common-variant/common-disease hypothesis, frequent functional polymorphisms are the best candidates for disease-susceptibility alleles. Implicitly, we also assume that disease-susceptibility alleles are preferentially transmitted from parents to the affected offspring and that this effect can be captured by the...

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Identifiers

PMID: 12058344
DOI: 10.1086/341345
PMCID: PMC384979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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