Article
Making the most of case-mother/control-mother studies.
American journal of epidemiology - 1 Sept 2008
Shi M, Umbach D M, Vermeulen S H, Weinberg C R
Abstract excerpt
The prenatal environment plays an important role in many conditions, particularly those with onset early in life, such as childhood cancers and birth defects. Because both maternal and fetal genotypes can influence risk, investigators sometimes use a case-mother/control-mother design, with mother-offspring pairs as the unit of analysis, to study genetic factors. Risk models should account for both the maternal...
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