Article
Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype.
Neurology - 26 Jun 2001
Houlden H, Baker M, Morris H R, MacDonald N, Pickering-Brown S, Adamson J, Lees A J, Rossor M N, Quinn N P, Kertesz A, Khan M N, Hardy J, Lantos P L, St George-Hyslop P, Munoz D G, Mann D, Lang A E, Bergeron C, Bigio E H, Litvan I, Bhatia K P, Dickson D, Wood N W, Hutton M
Abstract excerpt
OBJECTIVE: To analyze the association of polymorphisms in the tau gene with pathologically confirmed corticobasal degeneration (CBD). BACKGROUND: The authors previously described an extended tau haplotype (H1) that covers the human tau gene and is associated with the development of progressive supranuclear palsy (PSP). The authors now extend this analysis to CBD, a neurodegenerative condition with clinical and...
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