Article
Mutations causing neurodegenerative tauopathies.
Biochimica et biophysica acta - 3 Jan 2005
Goedert Michel, Jakes Ross
Abstract excerpt
Tau is the major component of the intracellular filamentous deposits that define a number of neurodegenerative diseases. They include the largely sporadic Alzheimer's disease (AD), progressive supranuclear palsy, corticobasal degeneration, Pick's disease and argyrophilic grain disease, as well as the inherited frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). For a long time, it was...
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