Article
Case-Control study of the extended tau gene haplotype in Parkinson's disease.
Annals of neurology - 1 Nov 2001
Maraganore D M, Hernandez D G, Singleton A B, Farrer M J, McDonnell S K, Hutton M L, Hardy J A, Rocca W A
Abstract excerpt
We investigated the association of Parkinson's disease with tau gene haplotypes. In a sample of 319 unrelated Parkinson's disease patients and 196 control subjects, we observed an increased risk of Parkinson's disease for persons with the H1/H1 genotype (odds ratio = 1.5; 95% confidence interval: 0.98-2.23); however, the finding was not statistically significant. The results remained similar after adjusting for...
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