Article
Structure of human phosphatidylcholine transfer protein in complex with its ligand.
Nature structural biology - 1 Jul 2002
Roderick Steven L, Chan Wayne W, Agate Diana S, Olsen Laurence R, Vetting Matt W, Rajashankar K R, Cohen David E
Abstract excerpt
Phosphatidylcholines (PtdChos) comprise the most common phospholipid class in eukaryotic cells. In mammalian cells, these insoluble molecules are transferred between membranes by a highly specific phosphatidylcholine transfer protein (PC-TP) belonging to the steroidogenic acute regulatory protein related transfer (START) domain superfamily of hydrophobic ligand-binding proteins. The crystal structures of human...
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