Article
Steroidogenic acute regulatory protein: an update on its regulation and mechanism of action.
Archives of medical research - 1 Jan 2000
Christenson L K, Strauss J F
Abstract excerpt
Steroidogenic acute regulatory (StAR) protein controls the rate-limiting step in steroidogenesis: the transport of cholesterol from the outer to the inner mitochondrial membrane. Early studies indicated that rate of transcription of the StAR gene is a primary determinant of steroidogenesis. The transcription factors that govern basal and cAMP-dependent StAR expression are reviewed, as are new findings regarding...
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