Article
Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells.
Traffic (Copenhagen, Denmark) - 1 Sept 2008
Shadan Sadaf, Holic Roman, Carvou Nicolas, Ee Patrick, Li Michelle, Murray-Rust Judith, Cockcroft Shamshad
Abstract excerpt
Of many lipid transfer proteins identified, all have been implicated in essential cellular processes, but the activity of none has been demonstrated in intact cells. Among these, phosphatidylinositol transfer proteins (PITP) are of particular interest as they can bind to and transfer phosphatidylinositol (PtdIns)--the precursor of important signalling molecules, phosphoinositides--and because they have essential...
Topics
- 2,2'-Dipyridyl
- Animals
- Binding Sites
- COS Cells
- Cell Membrane
- Chlorocebus aethiops
- Cytosol
- Disulfides
- Endoplasmic Reticulum
- Escherichia coli
- Ethylmaleimide
- Golgi Apparatus
- HL-60 Cells
- Humans