Article
eIF4E is an important determinant of adhesion and pseudohyphal growth of the yeast S. cerevisiae.
PloS one - 1 Jan 2012
Ross Daniela, Saxena Manisha, Altmann Michael
Abstract excerpt
eIF4E, the cytoplasmatic cap-binding protein, is required for efficient cap-dependent translation. We have studied the influence of mutations that alter the activity and/or expression level of eIF4E on haploid and diploid cells in the yeast S. cerevisiae. Temperature-sensitive eIF4E mutants with reduced levels of expression and reduced cap-binding affinity clearly show a loss in haploid adhesion and diploid...
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