Article
mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E.
Molecular and cellular biology - 1 Nov 2000
Schwartz D C, Parker R
Abstract excerpt
A major pathway of eukaryotic mRNA turnover occurs by deadenylation-dependent decapping that exposes the transcript to 5'-->3' exonucleolytic degradation. A critical step in this pathway is decapping, since removal of the cap structure permits 5'-->3' exonucleolytic digestion. Based on alteration...
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