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Article

mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E.

Molecular and cellular biology - 1 Nov 2000

Schwartz D C, Parker R

Abstract excerpt

A major pathway of eukaryotic mRNA turnover occurs by deadenylation-dependent decapping that exposes the transcript to 5'-->3' exonucleolytic degradation. A critical step in this pathway is decapping, since removal of the cap structure permits 5'-->3' exonucleolytic digestion. Based on alterations in mRNA decay rate from strains deficient in translation initiation, it has been proposed that the decapping rate is...

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Identifiers

PMID: 11027264
DOI: 10.1128/MCB.20.21.7933-7942.2000
PMCID: PMC86404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E.PMID 11027264Read ↗

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