Article
Control of intercalation is cell-autonomous in the notochord of Ciona intestinalis.
Developmental biology - 15 Jun 2002
Keys David N, Levine Michael, Harland Richard M, Wallingford John B
Abstract excerpt
Dishevelled signaling plays a critical role in the control of cell intercalation during convergent extension in vertebrates. This study presents evidence that Dishevelled serves a similar function in the Ciona notochord. Embryos transgenic for mutant Dishevelled fail to elongate their tails, and notochord cells fail to intercalate, though notochord cell fates are unaffected. Analysis of mosaic transgenics...
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