Article
Ascidian prickle regulates both mediolateral and anterior-posterior cell polarity of notochord cells.
Current biology : CB - 11 Jan 2005
Jiang Di, Munro Edwin M, Smith William C
Abstract excerpt
The ascidian notochord follows a morphogenetic program that includes convergent extension (C/E), followed by anterior-posterior (A/P) elongation [1-4]. As described here, developing notochord cells show polarity first in the mediolateral (M/L) axis during C/E, and subsequently in the A/P axis during elongation. Previous embryological studies [3] have shown that contact with neighboring tissues is essential for...
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