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Article

Pretest prediction of BRCA1 or BRCA2 mutation by risk counselors and the computer model BRCAPRO.

Journal of the National Cancer Institute - 5 Jun 2002

Euhus David M, Smith Kristin C, Robinson Linda, Stucky Amy, Olopade Olufunmilayo I, Cummings Shelly, Garber Judy E, Chittenden Anu, Mills Gordon B, Rieger Paula, Esserman Laura, Crawford Beth, Hughes Kevin S, Roche Connie A, Ganz Patricia A, Seldon Joyce, Fabian Carol J, Klemp Jennifer, Tomlinson Gail

Abstract excerpt

BACKGROUND: Because BRCA gene mutation testing is costly, occasionally uninformative, and frequently associated with ethical and legal issues, careful patient selection is required prior to testing. Estimation of BRCA gene mutation probability is an important component of pretest counseling, but the accuracy of these estimates is currently unknown. We measured the performance of eight cancer risk counselors and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12048272
DOI: 10.1093/jnci/94.11.844

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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